 | Chris Pratt | .... | Peter Quill |
 | Zoe Saldana | .... | Gamora |
 | Dave Bautista | .... | Drax |
 | Vin Diesel | .... | Groot (Stimme) |
 | Bradley Cooper | .... | Rocket (Stimme) |
 | Lee Pace | .... | Ronan |
 | Michael Rooker | .... | Yondu Udonta |
 | Karen Gillan | .... | Nebula |
 | Djimon Hounsou | .... | Korath |
 | John C. Reilly | .... | Corpsman Dey |
 | Glenn Close | .... | Nova Prime |
 | Benicio Del Toro | .... | The Collector |
 | Laura Haddock | .... | Meredith Quill |
 | Sean Gunn | .... | Kraglin / On Set Rocket |
 | Peter Serafinowicz | .... | Denarian Saal |
 | Christopher Fairbank | .... | The Broker |
 | Krystian Godlewski | .... | On Set Groot |
 | Wyatt Oleff | .... | Young Quill |
 | Gregg Henry | .... | Grandpa |
 | Janis Ahern | .... | Meredith's Mother |
 | Solomon Mousley | .... | Meredith's Brother |
 | Lindsay Morton | .... | Meredith's Best Friend |
 | Robert Firth | .... | Dr. Fitzgibbon |
 | Melia Kreiling | .... | Bereet |
 | Tom Proctor | .... | Horuz |
 | Nick Holmes | .... | Horuz's Mate |
 | Max Wrottesley | .... | Sacrifice Nova Corpsman |
 | Stan Lee | .... | Xandarian Ladies' Man |
 | Nicole Alexandra Shipley | .... | Pretty Xandarian |
 | Sharif Atkins | .... | Nova Arresting Pilot |
 | Brendan Fehr | .... | Corpsman Dey's Partner |
 | Tomas Arana | .... | Kree Ambassador |
 | Mikaela Hoover | .... | Nova Prime's Assistant |
 | Emmett J. Scanlan | .... | Head Riot Guard |
 | Dominic Grant | .... | Angry Guard |
 | Spencer Wilding | .... | Mean Guard |
 | Alison Lintott | .... | Sad Woman with Horns |
 | Alexis Rodney | .... | Moloka Dar |
 | Nathan Fillion | .... | Monstrous Inmate (Stimme) |
 | Keeley Forsyth | .... | Mottled Prisoner |
 | Frank Gilhooley | .... | Burly Prisoner |
 | Alexis Denisof | .... | The Other |
 | Enzo Cilenti | .... | Watchtower Guard |
 | Richard Katz | .... | One Legged Prisoner |
 | Enoch Frost | .... | Rifle Guard |
 | Ronan Summers | .... | 'Drop the Leg' Guard |
 | Ophelia Lovibond | .... | Carina |
 | Laura Ortiz | .... | Tortured Pink Girl |
 | Marama Corlett | .... | Pit Boss |
 | Rosie Jones | .... | Lady of the Boot of Jemiah |
 | Abidemi Sobande | .... | Lady of the Boot of Jemiah |
 | Alex Rose | .... | Lady of the Boot of Jemiah |
 | Ekaterina Zalitko | .... | Lady of the Boot of Jemiah |
 | Emily Redding | .... | Lady of the Boot of Jemiah |
 | Fred | .... | Cosmo the Space Dog |
 | Stephen Blackehart | .... | Knowhere Dispatcher |
 | Jennifer Moylan-Taylor | .... | Sad Krylorian Girl |
 | Bruce Mackinnon | .... | One-Eyed Ravager |
 | Ralph Ineson | .... | Ravager Pilot |
 | Rob Zombie | .... | Ravager Navigator (Stimme) |
 | Naomi Ryan | .... | Nova Centurion |
 | John Brotherton | .... | Nova Starblaster Pilot |
 | Graham Shiels | .... | Alien Nova Pilot |
 | James Gunn | .... | Maskless Sakaaran / Dancing Groot / Sakaarans |
 | Douglas Robson | .... | Maskless Sakaaran |
 | Rachel Cullen | .... | Corpsman Dey's Wife |
 | Isabella Poynton | .... | Corpsman Dey's Daughter |
 | Imogen Poynton | .... | Corpsman Dey's Daughter |
 | David Yarovesky | .... | Goth Ravager |
 | Miriam Lucia | .... | Crying Xandarian Citizen |
 | Raed Abbas | .... | Ravager (uncredited) |
 | Adrian Allan | .... | Nova Corps Soldier / Policeman (uncredited) |
 | Freddie Andrews | .... | Traveler (uncredited) |
 | Habib Anibaba | .... | Nova Corps Millennian (uncredited) |
 | Eddie Bammeke | .... | Prisoner (uncredited) |
 | Helen Banks | .... | Prisoner (uncredited) |
 | Tyler Bates | .... | Ravager Pilot (uncredited) |
 | Marco Biagioli | .... | Technician (uncredited) |
 | Richard Blenkiron | .... | Exolon Monk (uncredited) |
 | David Booth | .... | Knowhere Miner (uncredited) |
 | Josh Brolin | .... | Thanos (uncredited) |
 | Joanna Chamberlain | .... | Beautiful Alien (uncredited) |
 | Bern Collaço | .... | Morag Citizen (uncredited) |
 | Rowan Cox | .... | Prisoner (uncredited) |
 | Alysson Da Silva | .... | Prisoner (uncredited) |
 | Marianna Dean | .... | Peter's Aunt (uncredited) |
 | Wayne Devlin | .... | Nova Guard (uncredited) |
 | Simara Dixon | .... | Xandarian Alien (uncredited) |
 | Jadey Duffield | .... | Xander (uncredited) |
 | Barny DuPlessis | .... | Flocks Alien Prisoner (uncredited) |
 | Mark Falvo | .... | Prisoner (uncredited) |
 | Kristen Fick | .... | Alien Prisoner (uncredited) |
 | Gracie Fitch | .... | Groot's Flower Girl (uncredited) |
 | Melissa Galloway | .... | Hospital Visitor (uncredited) |
 | Alex Gillison | .... | Xandar Traveler (uncredited) |
 | Sophie Gooding | .... | Xandar Citizen (uncredited) |
 | Henry Goodrich | .... | Crane Operator (uncredited) |
 | Seth Green | .... | Howard the Duck (uncredited, Stimme) |
 | Victoria Gugenheim | .... | Kallulian Kyln Prisoner (uncredited) |
 | Simon Hatt | .... | Prisoner / Sakaarans (uncredited) |
 | Lindy Hennessy | .... | Family Mourner (uncredited) |
 | Leigh Holland | .... | Alien Prisoner (uncredited) |
 | Pete Buzzsaw Holland | .... | Prisoner (uncredited) |
 | James Walton Ingham | .... | Knowhere Miner (uncredited) |
 | Lee Edward Jones | .... | Exolon Monk (uncredited) |
 | Lloyd Kaufman | .... | Prisoner (uncredited) |
 | Jonathan Lipow | .... | Sakaarans (uncredited, Stimme) |
 | Matt Lott | .... | Prisoner (uncredited) |
 | David L. Marston | .... | Prison Guard (uncredited) |
 | Matthew David McCarthy | .... | Prison Alien (uncredited) |
 | Stephen McDade | .... | Prisoner (uncredited) |
 | Erica Melargo | .... | Xandar Resident (uncredited) |
 | Serhat Metin | .... | Nova Corps Officer (uncredited) |
 | Georgiana Mihai | .... | Exolon Monk (uncredited) |
 | Sandeep Mohan | .... | Exolon Monk (uncredited) |
 | Nigel Murfitt | .... | Neo-Nazi Prisoner (uncredited) |
 | Emeson Nwolie | .... | Knowhere Miner (uncredited) |
 | Oreo | .... | Rocket Racoon Facial Reference (uncredited) |
 | Louise Port | .... | Nova Yellow Alien Worker (uncredited) |
 | Joseph Quartson | .... | Miner (uncredited) |
 | Diezel Ramos | .... | Prison Guard (uncredited) |
 | Deborah Rosan | .... | Alien 1 (uncredited) |
 | Gordon Round | .... | Prison Guard (uncredited) |
 | Steve Saunders | .... | Kyln Prisoner (uncredited) |
 | Andrew Scott-Marshall | .... | Alien Prisoner (uncredited) |
 | Julian Seager | .... | Prisoner (uncredited) |
 | Clem So | .... | Kyln Prisoner (uncredited) |
 | Adrian South | .... | Xandar Resident (uncredited) |
 | Peter Theobalds | .... | Kyln Prisoner (uncredited) |
 | Wesley Von Spears | .... | Holographic Dog (uncredited) |
 | Paul Warren | .... | Alien (uncredited) |
 | Tatiana Zarubova | .... | Female Prison Guard (uncredited) |